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  Replied by UEndocrine Staff on Monday, January 02 2012, 05:00 PM

  For example, Dapagliflozin lowers A1C by up to:
  
  -0.8% in monotherapy at the 5 mg dose.
  -0.84% at 10 mg when added to metformin
  -0.82% at 10 mg when added to sulfonylurea
  -0.97% at 10 mg when added on to pioglitazone
  -0.90% at 10 mg when added on to insulin
  
  I have attached a graph of these results at bottom of this response.

  Attachments:

  • Dapagliflozin - Dose-dependent A1C Reductions at Week 24.jpg