Hello, You have raised a very interesting phenomenon. Patients with impaired renal function, particularly if moderate to severe, have lower red-cell survival. Since it takes time to glycate hemoglobin, the reduced lifespan of the RBC might lead to decreased time exposure to a high glucose environment and therefore lower A1C. Of course, we ar...

Very useful post!...

Dapagliflozin lowers A1C by up to: -0.8% in monotherapy at the 5 mg dose. -0.84% at 10 mg when added to metformin -0.82% at 10 mg when added to sulfonylurea -0.97% at 10 mg when added on to pioglitazone -0.90% at 10 mg when added on to insulin I have attached a graph of these results at bottom of this response....

What is the approximate efficacy of SGLT inhibitors when using to lower blood sugar?...

{ppgallery}slides/general/periods{/ppgallery} test {gallery}sglt{/gallery}...

Test {ppgallery}slides/general/periods{/ppgallery}...